![C13H13NO5 1H-Pyrano[3,4-f]indolizin-3,6,10(4H)-trion, 4-etil-7,8-dihidro-4- gidroksi-, (4S)- (9CI, ACI) H319, H302](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C13H13NO5 1H-Pyrano[3,4-f]indolizin-3,6,10(4H)-trion, 4-etil-7,8-dihidro-4- gidroksi-, (4S)- (9CI, ACI) H319, H302 Tavsiya etilgan rasm](https://cdn.globalso.com/nvchem/C13H13NO5-1H-Pyrano.jpg)
C13H13NO5 1H-Pyrano[3,4-f]indolizin-3,6,10(4H)-trion, 4-etil-7,8-dihidro-4- gidroksi-, (4S)- (9CI, ACI) H319, H302
| Asosiy jismoniy xususiyatlar | Qiymat | Vaziyat |
| Molekulyar og'irlik | 263.25 | - |
| Erish nuqtasi (eksperimental) | 177,1-178,3 ° S gacha | - |
| Qaynoq nuqtasi (taxmin qilingan) | 666,6±55,0 °C | Matbuot: 760 Torr |
| Zichlik (taxmin qilingan) | 1,50±0,1 g/sm3 | Harorat: 20 °C; Matbuot: 760 Torr |
| pKa (taxmin qilingan) | 11,20±0,20 | Eng kislotali harorat: 25 °C |
Kanonik tabassum O=C1C2=C(C=C3C(=O)CCN13)C(O)(C(=O)OC2)CC
Izomerik tabassum C(C)[C@]1(O)C2=C(C(=O)N3C(=C2)C(=O)CC3)COC1=O
InChI
InChI=1S/C13H13NO5/c1-2-13(18)8-5-9-10(15)3-4-14(9)11(16)7(8)6-19-12(13)17/ h5,18H,2-4,6H2,1H3/t13-/m0/s1
InChI kaliti
IGKWOGMVAOYVSJ-ZDUSSCGKSA-N
5 Ushbu moddaning boshqa nomlari
(4S) -4-Etil-7,8-dihidro-4-gidroksi-1H-pirano[3,4-f]indolizin-3,6,10 (4H)-trion (ACI); 1H-Pyrano[3,4-f]indolizin-3,6,10(4H)-trion, 4-etil-7,8-dihidro-4-gidroksi-, (S)- (ZCI); (4S) -4-Etil-4-gidroksi-7,8-dihidro-1H-pirano [3,4-f] indolizin-3,6,10 (4H) trion; (4S) -4-Etil-4-
gidroksi-7,8-dihidro-1H-pirano[3,4-f]indolizin-3,6,10-trion; (S) -4-Etil-4-gidroksi-7,8-dihidro-1H-pirano[3,4-f]indolizin-3,6,10 (4H)-trion
| Xususiyatlari mavjud |
| Optik va tarqalish |
| Termal |
Optik va tarqalish
| Mulk | Qiymat | Vaziyat | Manba |
| Optik aylanish kuchi | +120,6 daraja | c: 0,62 g/100 ml; Erituvchi: xloroform | (1) IC |
| Optik aylanish kuchi | +120,57 daraja | c: 0,62 g/100 ml; Erituvchi: Xloroform; Harorat: 20 °C | (2) IC |
| Optik aylanish kuchi | +119,57 daraja | c: 1,0 g/100 ml; Erituvchi: Xloroform; l: 589,3 nm; Harorat: 25 °C | (3) CAS |
| Optik aylanish kuchi | +119,57 daraja·ml/g·dm | c: 1,0 g/100 ml; Erituvchi: Xloroform; l: natriy D liniyasi; Harorat: 25 °C | (4) CAS |
| Optik aylanish kuchi | +117,6 daraja | c: 0,56 g/100 ml; Erituvchi: Xloroform; Harorat: 23 °C | (5) IC |
| Optik aylanish kuchi | +116,14 daraja·ml/g·dm | c: 1,0 g/100 ml; Erituvchi: Xloroform; l: natriy D liniyasi; Harorat: 26 °C | (4) CAS |
| Optik aylanish kuchi | +96 daraja | c: 0,40 g/100 ml; Harorat: 21 °C | (6) IC |
| Optik aylanish kuchi | +77,8 daraja | c: 0,62 g/100 ml; Erituvchi: Xloroform; l: 589,3 nm; Harorat: 25 °C | (7) CAS |
(1) Terasava, Xirofumi; Chemical & Pharmaceutical Bulletin, (1989), 37(12), 3382-5, CAplus
(2) Tagava, Xiroaki; EP220601, A1, 1987, CAplus
(3) Henegar, Kevin E.; Organik kimyo jurnali, (1997), 62(19), 6588-6597, CAplus
(4) Vatanabe, Tatsuya; Kimyo - Osiyo jurnali, (2013), 8(3), 630-638, CAplus
(5) Ejima, Akio; Kimyoviy jamiyat jurnali, Perkin tranzaksiyalari 1: Organik va bio-organik kimyo (1972-1999), (1990)(1), 27-31, CAplus
(6) Vani, Mansux C.; Tibbiy kimyo jurnali, (1987), 30(12), 2317-19, CAplus
(7) Kuang, Yun-Yan; Helvetica Chimica Acta, (2010), 93(10), 2094-2099, CAplus
Termal
| Mulk | Qiymat | Vaziyat | Manba | |
| Erish nuqtasi | 183-185 °C (parchalanish) | (1) CAS | ||
| Erish nuqtasi | 177,1-178,3 ° S gacha | (2) CAS | ||
| Erish nuqtasi | 176-177 °C (parchalanish) | (3) IC | ||
| Erish nuqtasi | 169-170 ° S | Erituvchi: | Etil asetat | (4) IC |
(1) Kuang, Yun-Yan; Helvetica Chimica Acta, (2010), 93(10), 2094-2099, CAplus
(2) Henegar, Kevin E.; Organik kimyo jurnali, (1997), 62(19), 6588-6597, CAplus
(3) Ejima, Akio; Kimyoviy jamiyat jurnali, Perkin tranzaksiyalari 1: Organik va bio-organik kimyo (1972-1999), (1990)(1), 27-31, CAplus
(4) Vani, Mansux C.; Tibbiy kimyo jurnali, (1987), 30(12), 2317-19, CAplus
Spektrlar mavjud
1H NMR
Massa
| Xususiyatlari mavjud |
| Biologik |
| Kimyoviy |
| Zichlik |
| Lipinskiy |
| Tuzilishi bilan bog'liq |
| Termal |
Biologik
| Mulk | Qiymat | Vaziyat | Manba |
| Biokonsentratsiya omili | 1.0 | pH 1; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1.0 | pH 2; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1.0 | pH 3; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1.0 | pH 4; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1.0 | pH 5; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1.0 | pH 6; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1.0 | pH 7; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1.0 | pH 8; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1.0 | pH 9; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1.0 | pH 10; Harorat: 25 °C | (1) ACD |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
Kimyoviy
| Mulk | Qiymat | Vaziyat | Manba |
| Koch | 7.37 | pH 1; Harorat: 25 °C | (1) ACD |
| Koch | 7.37 | pH 2; Harorat: 25 °C | (1) ACD |
| Koch | 7.37 | pH 3; Harorat: 25 °C | (1) ACD |
| Koch | 7.37 | pH 4; Harorat: 25 °C | (1) ACD |
| Koch | 7.37 | pH 5; Harorat: 25 °C | (1) ACD |
| Koch | 7.37 | pH 6; Harorat: 25 °C | (1) ACD |
| Koch | 7.37 | pH 7; Harorat: 25 °C | (1) ACD |
| Mulk | Qiymat | Vaziyat | Manba |
| Koch | 7.37 | pH 8; Harorat: 25 °C | (1) ACD |
| Koch | 7.33 | pH 9; Harorat: 25 °C | (1) ACD |
| Koch | 6.94 | pH 10; Harorat: 25 °C | (1) ACD |
| logD | -0,94 | pH 1; Harorat: 25 °C | (1) ACD |
| logD | -0,94 | pH 2; Harorat: 25 °C | (1) ACD |
| logD | -0,94 | pH 3; Harorat: 25 °C | (1) ACD |
| logD | -0,94 | pH 4; Harorat: 25 °C | (1) ACD |
| logD | -0,94 | pH 5; Harorat: 25 °C | (1) ACD |
| logD | -0,94 | pH 6; Harorat: 25 °C | (1) ACD |
| logD | -0,94 | pH 7; Harorat: 25 °C | (1) ACD |
| logD | -0,94 | pH 8; Harorat: 25 °C | (1) ACD |
| logD | -0,94 | pH 9; Harorat: 25 °C | (1) ACD |
| logD | -0,96 | pH 10; Harorat: 25 °C | (1) ACD |
| logP | -0,936±0,842 | Harorat: 25 °C | (1) ACD |
| Massaning ichki eruvchanligi | 371 g/l | Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 371 g/l | pH 1; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 371 g/l | pH 2; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 371 g/l | pH 3; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 371 g/l | pH 4; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 371 g/l | pH 5; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 371 g/l | pH 6; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 371 g/l | pH 7; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 371 g/l | pH 8; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 371 g/l | pH 9; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 392 g/l | pH 10; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 371 g/l | Bufersiz suv pH 5,53; Harorat: 25 °C | (1) ACD |
| Molar ichki eruvchanligi | 1,41 mol/l | Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,41 mol/l | pH 1; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,41 mol/l | pH 2; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,41 mol/l | pH 3; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,41 mol/l | pH 4; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,41 mol/l | pH 5; Harorat: 25 °C | (1) ACD |
| Mulk | Qiymat | Vaziyat | Manba | |
| Molyar eruvchanlik | 1,41 mol/l | pH 6; Harorat: 25 °C | (1) ACD | |
| Molyar eruvchanlik | 1,41 mol/l | pH 7; Harorat: 25 °C | (1) ACD | |
| Molyar eruvchanlik | 1,41 mol/l | pH 8; Harorat: 25 °C | (1) ACD | |
| Molyar eruvchanlik | 1,41 mol/l | pH 9; Harorat: 25 °C | (1) ACD | |
| Molyar eruvchanlik | 1,49 mol/l | pH 10; Harorat: 25 °C | (1) ACD | |
| Molyar eruvchanlik | 1,41 mol/l | Bufersiz suv pH 5,53; Harorat: 25 °C | (1) ACD | |
| Molekulyar og'irlik | 263.25 | |||
| pKa | 11,20±0,20 | Eng kislotali harorat: 25 °C | (1) ACD | |
| pKa | -2,24±0,40 | Eng asosiy harorat: 25 °C | (1) ACD | |
| Bug 'bosimi | 1,29 x 10-20 | Torr | Harorat: 25 °C | (1) ACD |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
Zichlik
| Mulk | Qiymat | Vaziyat | Manba |
| Zichlik | 1,50±0,1 g/sm3 | Harorat: 20 °C; Matbuot: 760 Torr | (1) ACD |
| Molyar hajm | 174,8±5,0 sm3/mol | Harorat: 20 °C; Matbuot: 760 Torr | (1) ACD |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
Lipinskiy
| Mulk | Qiymat | Vaziyat | Manba |
| Erkin aylanadigan obligatsiyalar | 2 | (1) ACD | |
| H qabul qiluvchilar | 6 | (1) ACD | |
| H Donorlar | 1 | (1) ACD | |
| H Donor/akseptor summasi | 7 | (1) ACD | |
| logP | -0,936±0,842 | Harorat: 25 °C | (1) ACD |
| Molekulyar og'irlik | 263.25 |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
Tuzilishi bilan bog'liq
| Mulk | Qiymat | Vaziyat | Manba |
| Qutb yuzasi maydoni | 83,9 A2 | (1) ACD | |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
Termal
| Mulk | Qiymat | Vaziyat | Manba |
| Qaynash nuqtasi | 666,6±55,0 °C | Matbuot: 760 Torr | (1) ACD |
| Bug'lanish entalpiyasi | 112,17±6,0 kJ/mol | Matbuot: 760 Torr | (1) ACD |
| O't olish nuqtasi | 357,0±31,5 °C | (1) ACD |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
Spektrlar mavjud
1H NMR
13C NMR
| Kod | Xavf haqida bayonot | Manba |
| H319 | Ko'zning jiddiy tirnash xususiyati keltirib chiqaradi | Yevropa kimyo agentligi (ECHA) tasnifi va yorliqlash inventarizatsiyasi - Xabardor qilingan tasnif va yorliqlash - eng keng tarqalgan bildirishnomalar, Yevropa kimyo agentligi (ECHA) tasnifi va etiketkalash inventarizatsiyasi - tasdiqlangan tasnif va etiketkalash - eng jiddiy bildirishnomalar |
| H302 | Yutib yuborilsa zararli | Yevropa kimyo agentligi (ECHA) tasnifi va yorliqlash inventarizatsiyasi - Xabardor qilingan tasnif va yorliqlash - eng keng tarqalgan bildirishnomalar, Yevropa kimyo agentligi (ECHA) tasnifi va etiketkalash inventarizatsiyasi - tasdiqlangan tasnif va etiketkalash - eng jiddiy bildirishnomalar |
Maxfiy biznes ma'lumotlari: ommaviy
| Normativ sinonimlar | ||
| (S) -4-etil-4-gidroksi-7,8-dihidro-1H-piranno(3,4-f)indolizin-3,6,10(4H)-trion | - | frantsuz |
| (S) -4-etil-4-gidroksi-7,8-dihidro-1H-piranno[3,4-f]indolizin-3,6,10(4H)-trion | - | frantsuz |
| (S) -4-Etil-4-gidroksi-7,8-dihidro-1H-pirano (3,4-f) indolizin-3,6,10 (4H)-trion | - | Daniya, nemis |
| (S) -4-etil-4-gidroksi-7,8-dihidro-1H-pirano(3,4-f)indolizin-3,6,10(4H)-trion | - | golland |
| (S) -4-Etil-4-gidroksi-7,8-dihidro-1H-pirano[3,4-f]indolizin-3,6,10(4H)-trion | - | Daniya, nemis |
| (S) -4-etil-4-gidroksi-7,8-dihidro-1H-pirano[3,4-f]indolizin-3,6,10(4H)-trion | - | golland |
| (S) -4-etil-4-gidroksi-7,8-dihidro-1H-pirano[3,4-f]indolizin-3,6,10(4H)-trion | - | - |
| (S)-4-etil-4-hidroxi-7,8-dihidro-1H-pirano(3,4-f)indolizina-3,6,10(4H)-triona | - | Portugal, ispan |
| (S) -4-etil-4-hidroxi-7,8-dihidro-1H-pirano[3,4-f]indolizina-3,6,10(4H)-triona | - | Portugal, ispan |
| (S)-4-etil-4-idrossi-7,8-diidro-1H-pirano(3,4-f)indolizin-3,6,10(4H)-trion | - | italyancha |
| (S) -4-etil-4-idrossi-7,8-diidro-1H-pirano[3,4-f]indolizin-3,6,10(4H)-trion | - | italyancha |
| (S) -4-etil-4-gidroksi-7,8-dihidro-1H-pirano (3,4-f) indolizin-3,6,10 (4H)-trion | - | shvedcha |
| (S) -4-etil-4-gidroksi-7,8-dihidro-1H-pirano[3,4-f]indolizin-3,6,10(4H)-trion | - | shvedcha |
| (S)-4-etiyli-4-gidroksi-7,8-dihidro-1H-pirano(3,4-f)indolitsiini-3,6,10(4H)-trioni | - | fin |
| (S) -4-etiyli-4-gidroksi-7,8-dihidro-1H-pirano[3,4-f]indolitsiini-3,6,10(4H)-trioni | - | fin |
Tafsilotlar mamlakat/xalqaro va boshqa roʻyxatlar boʻyicha
Uyg'unlashtirilgan tarif kodi: 293499 Mamlakat/mintaqa ma'lumotlari mavjud
Evropa Ittifoqining qisqacha mazmuni
Evropa Ittifoqi bayroqlari
Evropa Ittifoqining bojxona kodi CN: 29349990
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